Characterization of an anti-fetal AChR monoclonal antibody isolated from a myasthenia gravis patient
We report here the sequence and functional characterization of a recombinantly expressed autoantibody (mAb 131) previously isolated from a myasthenia gravis patient by immortalization of thymic B cells using Epstein-Barr virus and TLR9 activation. The antibody is characterized by a high degree of so...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663942/ https://www.ncbi.nlm.nih.gov/pubmed/29089519 http://dx.doi.org/10.1038/s41598-017-14350-8 |