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Chromatin interaction networks revealed unique connectivity patterns of broad H3K4me3 domains and super enhancers in 3D chromatin

Broad domain promoters and super enhancers are regulatory elements that govern cell-specific functions and harbor disease-associated sequence variants. These elements are characterized by distinct epigenomic profiles, such as expanded deposition of histone marks H3K27ac for super enhancers and H3K4m...

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Detalles Bibliográficos
Autores principales: Thibodeau, Asa, Márquez, Eladio J., Shin, Dong-Guk, Vera-Licona, Paola, Ucar, Duygu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663946/
https://www.ncbi.nlm.nih.gov/pubmed/29089515
http://dx.doi.org/10.1038/s41598-017-14389-7