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Chromatin interaction networks revealed unique connectivity patterns of broad H3K4me3 domains and super enhancers in 3D chromatin
Broad domain promoters and super enhancers are regulatory elements that govern cell-specific functions and harbor disease-associated sequence variants. These elements are characterized by distinct epigenomic profiles, such as expanded deposition of histone marks H3K27ac for super enhancers and H3K4m...
Autores principales: | Thibodeau, Asa, Márquez, Eladio J., Shin, Dong-Guk, Vera-Licona, Paola, Ucar, Duygu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663946/ https://www.ncbi.nlm.nih.gov/pubmed/29089515 http://dx.doi.org/10.1038/s41598-017-14389-7 |
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