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Modeling Group B Streptococcus and Blood-Brain Barrier Interaction by Using Induced Pluripotent Stem Cell-Derived Brain Endothelial Cells

Bacterial meningitis is a serious infection of the central nervous system (CNS) that occurs after bacteria interact with and penetrate the blood-brain barrier (BBB). The BBB is comprised of highly specialized brain microvascular endothelial cells (BMECs) that function to separate the circulation fro...

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Detalles Bibliográficos
Autores principales: Kim, Brandon J., Bee, Olivia B., McDonagh, Maura A., Stebbins, Matthew J., Palecek, Sean P., Doran, Kelly S., Shusta, Eric V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663983/
https://www.ncbi.nlm.nih.gov/pubmed/29104935
http://dx.doi.org/10.1128/mSphere.00398-17