Targeted dianthin is a powerful toxin to treat pancreatic carcinoma when applied in combination with the glycosylated triterpene SO1861

Targeted cancer therapy provides the basis for the arrest of tumor growth in aggressive pancreatic carcinoma; however, a number of protein‐based targeted toxins lack efficacy due to insufficient endosomal escape after being endocytosed. Therefore, we tested a fusion protein of the ribosome‐inactivat...

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Detalles Bibliográficos
Autores principales: Bhargava, Cheenu, Dürkop, Horst, Zhao, Xiangli, Weng, Alexander, Melzig, Matthias F., Fuchs, Hendrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664001/
https://www.ncbi.nlm.nih.gov/pubmed/28755527
http://dx.doi.org/10.1002/1878-0261.12115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664001/
https://www.ncbi.nlm.nih.gov/pubmed/28755527
http://dx.doi.org/10.1002/1878-0261.12115

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