Investigating the Interaction of Cyclic RGD Peptidomimetics with α(V)β(6) Integrin by Biochemical and Molecular Docking Studies

The interaction of a small library of cyclic RGD (Arg-Gly-Asp) peptidomimetics with α(V)β(6) integrin has been investigated by means of competitive solid phase binding assays to the isolated receptor and docking calculations in the crystal structure of the α(V)β(6) binding site. To this aim, a rigid...

Descripción completa

Detalles Bibliográficos
Autores principales: Civera, Monica, Arosio, Daniela, Bonato, Francesca, Manzoni, Leonardo, Pignataro, Luca, Zanella, Simone, Gennari, Cesare, Piarulli, Umberto, Belvisi, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664067/
https://www.ncbi.nlm.nih.gov/pubmed/28934103
http://dx.doi.org/10.3390/cancers9100128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664067/
https://www.ncbi.nlm.nih.gov/pubmed/28934103
http://dx.doi.org/10.3390/cancers9100128

Ejemplares similares