Folate-PEG Conjugates of a Far-Red Light-Activatable Paclitaxel Prodrug to Improve Selectivity toward Folate Receptor-Positive Cancer Cells

[Image: see text] We recently demonstrated the far-red light-activatable prodrug of paclitaxel (PTX), Pc-(L-PTX)(2). Upon illumination with a 690 nm laser, Pc-(L-PTX)(2) showed combinational cell killing from rapid photodynamic therapy damage by singlet oxygen, followed by sustained chemotherapy eff...

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Detalles Bibliográficos
Autores principales: Thapa, Pritam, Li, Mengjie, Karki, Radha, Bio, Moses, Rajaputra, Pallavi, Nkepang, Gregory, Woo, Sukyung, You, Youngjae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664141/
https://www.ncbi.nlm.nih.gov/pubmed/29104951
http://dx.doi.org/10.1021/acsomega.7b01105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664141/
https://www.ncbi.nlm.nih.gov/pubmed/29104951
http://dx.doi.org/10.1021/acsomega.7b01105

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