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Folate-PEG Conjugates of a Far-Red Light-Activatable Paclitaxel Prodrug to Improve Selectivity toward Folate Receptor-Positive Cancer Cells
[Image: see text] We recently demonstrated the far-red light-activatable prodrug of paclitaxel (PTX), Pc-(L-PTX)(2). Upon illumination with a 690 nm laser, Pc-(L-PTX)(2) showed combinational cell killing from rapid photodynamic therapy damage by singlet oxygen, followed by sustained chemotherapy eff...
Autores principales: | Thapa, Pritam, Li, Mengjie, Karki, Radha, Bio, Moses, Rajaputra, Pallavi, Nkepang, Gregory, Woo, Sukyung, You, Youngjae |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664141/ https://www.ncbi.nlm.nih.gov/pubmed/29104951 http://dx.doi.org/10.1021/acsomega.7b01105 |
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