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Small-Molecule-Based Self-Assembled Ligands for G-Quadruplex DNA Surface Recognition

[Image: see text] Most drugs are small molecules because of their attractive pharmacokinetics, manageable development and manufacturing, and effective binding into the concave crevices of bio-macromolecules. Despite these features, they often fall short when it comes to effectively recognizing the s...

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Detalles Bibliográficos
Autores principales: Rivera-Sánchez, María del C., García-Arriaga, Marilyn, Hobley, Gerard, Morales-de-Echegaray, Ana V., Rivera, José M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664172/
https://www.ncbi.nlm.nih.gov/pubmed/29104952
http://dx.doi.org/10.1021/acsomega.7b01255