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Aristolochic Acid-Induced Autophagy Promotes Epithelial-to-Myofibroblast Transition in Human Renal Proximal Tubule Epithelial Cells

Autophagy plays an essential role in cellular homeostasis in kidney. Previous studies have found that aristolochic acid (AA) can induce autophagy of renal tubular epithelial cells and epithelial-to-myofibroblast transition (EMT). However, the relationship between AA-induced autophagy and EMT is uncl...

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Detalles Bibliográficos
Autores principales: Man, Yu-Lin, Rui, Hong-Liang, Chen, Yi-Pu, Wang, Guo-qin, Sun, Li-Jun, Cheng, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664270/
https://www.ncbi.nlm.nih.gov/pubmed/29234448
http://dx.doi.org/10.1155/2017/9596256