Cargando…

Physiological Roles of DNA Double-Strand Breaks

Genomic integrity is constantly threatened by sources of DNA damage, internal and external alike. Among the most cytotoxic lesions is the DNA double-strand break (DSB) which arises from the cleavage of both strands of the double helix. Cells boast a considerable set of defences to both prevent and r...

Descripción completa

Detalles Bibliográficos
Autores principales: Khan, Farhaan A., Ali, Syed O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664317/
https://www.ncbi.nlm.nih.gov/pubmed/29181194
http://dx.doi.org/10.1155/2017/6439169