Toll-Like Receptor Ligand-Induced Liver Injury in D-Galactosamine-Sensitized Mice: Differences between TLR7/8 and TLR9 Ligands, Cytokine Patterns, and Cross-Tolerance Induction by TLR2 Ligand Pretreatment

Administration of Toll-like receptor ligands (TLRLs) is known to cause liver injury in D-galN-sensitized mice. In the present study, we aimed to complement preceding reports on the TLRL/D-galN system by analyzing comparisons among TLRLs, mouse strain dependence, effects on serum levels of cytokines,...

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Detalles Bibliográficos
Autor principal: Seki, Reiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664326/
https://www.ncbi.nlm.nih.gov/pubmed/29181417
http://dx.doi.org/10.1155/2017/9653793

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664326/
https://www.ncbi.nlm.nih.gov/pubmed/29181417
http://dx.doi.org/10.1155/2017/9653793

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