CD80 Expressed by CD8(+) T Cells Contributes to PD-L1-Induced Apoptosis of Activated CD8(+) T Cells

Tumor cells are capable of limiting antitumor CD8(+) T cell responses through their cell surface expression of PD-L1. In addition to PD-1 expressed by CD8(+) T cells, PD-L1 also binds to CD80 expressed by CD8(+) T cells. The influence of the PD-L1/CD80 interaction on CD8(+) T cell function has not b...

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Detalles Bibliográficos
Autores principales: Rollins, Meagan R., Gibbons Johnson, Rachel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664331/
https://www.ncbi.nlm.nih.gov/pubmed/29181416
http://dx.doi.org/10.1155/2017/7659462

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664331/
https://www.ncbi.nlm.nih.gov/pubmed/29181416
http://dx.doi.org/10.1155/2017/7659462

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