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CD80 Expressed by CD8(+) T Cells Contributes to PD-L1-Induced Apoptosis of Activated CD8(+) T Cells
Tumor cells are capable of limiting antitumor CD8(+) T cell responses through their cell surface expression of PD-L1. In addition to PD-1 expressed by CD8(+) T cells, PD-L1 also binds to CD80 expressed by CD8(+) T cells. The influence of the PD-L1/CD80 interaction on CD8(+) T cell function has not b...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Hindawi
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664331/ https://www.ncbi.nlm.nih.gov/pubmed/29181416 http://dx.doi.org/10.1155/2017/7659462 |