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Application of (19)F NMR Spectroscopy for Content Determination of Fluorinated Pharmaceuticals

A simple, rapid, and selective quantitative nuclear magnetic resonance spectroscopic method was evaluated for the determination of the content of fluorinated pharmaceuticals. (19)F NMR spectra were either obtained in dimethylsulfoxide-d(6) or aqueous buffer, using trifluoroacetic acid as internal st...

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Detalles Bibliográficos
Autores principales: Okaru, Alex O., Brunner, Tobias S., Ackermann, Svenja M., Kuballa, Thomas, Walch, Stephan G., Kohl-Himmelseher, Matthias, Lachenmeier, Dirk W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664369/
https://www.ncbi.nlm.nih.gov/pubmed/29181224
http://dx.doi.org/10.1155/2017/9206297