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RNA-seq Based Transcription Characterization of Fusion Breakpoints as a Potential Estimator for Its Oncogenic Potential

Based on high-throughput sequencing technology, the detection of gene fusions is no longer a big challenge but estimating the oncogenic potential of fusion genes remains challenging. Recent studies successfully applied machine learning methods and gene structural and functional features of fusion mu...

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Detalles Bibliográficos
Autores principales: Gu, Jian-lei, Chukhman, Morris, Lu, Yao, Liu, Cong, Liu, Shi-yi, Lu, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664375/
https://www.ncbi.nlm.nih.gov/pubmed/29181411
http://dx.doi.org/10.1155/2017/9829175