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The ADAMTS13(1239–1253) peptide is a dominant HLA-DR1-restricted CD4(+) T-cell epitope
Acquired thrombotic thrombocytopenic purpura is a rare and severe disease characterized by auto-antibodies directed against “A Disintegrin And Metalloproteinase with Thrombospondin type 1 repeats, 13(th) member" (ADAMTS13), a plasma protein involved in hemostasis. Involvement of CD4(+) T cells...
Autores principales: | , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ferrata Storti Foundation
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664387/ https://www.ncbi.nlm.nih.gov/pubmed/28751567 http://dx.doi.org/10.3324/haematol.2015.136671 |