Antigen receptor sequencing of paired bone marrow samples shows homogeneous distribution of acute lymphoblastic leukemia subclones

In B-cell precursor acute lymphoblastic leukemia, the initial leukemic cells share the same antigen receptor gene rearrangements. However, due to ongoing rearrangement processes, leukemic cells with different gene rearrangement patterns can develop, resulting in subclone formation. We studied leukem...

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Detalles Bibliográficos
Autores principales: Theunissen, Prisca M.J., van Zessen, David, Stubbs, Andrew P., Faham, Malek, Zwaan, Christian M., van Dongen, Jacques J.M., Van Der Velden, Vincent H.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664391/
https://www.ncbi.nlm.nih.gov/pubmed/28860343
http://dx.doi.org/10.3324/haematol.2017.171454

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664391/
https://www.ncbi.nlm.nih.gov/pubmed/28860343
http://dx.doi.org/10.3324/haematol.2017.171454

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