The novel isoxazoline ectoparasiticide lotilaner (Credelio™): a non-competitive antagonist specific to invertebrates γ-aminobutyric acid-gated chloride channels (GABACls)

BACKGROUND: The isoxazolines are a novel class of parasiticides that are potent inhibitors of γ-aminobutyric acid (GABA)-gated chloride channels (GABACls) and, to a lesser extent, of inhibitory glutamate-gated chloride channels (GluCls). Lotilaner (Credelio™), a novel representative of this chemical...

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Detalles Bibliográficos
Autores principales: Rufener, Lucien, Danelli, Vanessa, Bertrand, Daniel, Sager, Heinz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664438/
https://www.ncbi.nlm.nih.gov/pubmed/29089046
http://dx.doi.org/10.1186/s13071-017-2470-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664438/
https://www.ncbi.nlm.nih.gov/pubmed/29089046
http://dx.doi.org/10.1186/s13071-017-2470-4

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