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The influence of microRNAs and poly(A) tail length on endogenous mRNA–protein complexes

BACKGROUND: All mRNAs are bound in vivo by proteins to form mRNA–protein complexes (mRNPs), but changes in the composition of mRNPs during posttranscriptional regulation remain largely unexplored. Here, we have analyzed, on a transcriptome-wide scale, how microRNA-mediated repression modulates the a...

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Detalles Bibliográficos
Autores principales: Rissland, Olivia S., Subtelny, Alexander O., Wang, Miranda, Lugowski, Andrew, Nicholson, Beth, Laver, John D., Sidhu, Sachdev S., Smibert, Craig A., Lipshitz, Howard D., Bartel, David P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664449/
https://www.ncbi.nlm.nih.gov/pubmed/29089021
http://dx.doi.org/10.1186/s13059-017-1330-z