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The influence of microRNAs and poly(A) tail length on endogenous mRNA–protein complexes
BACKGROUND: All mRNAs are bound in vivo by proteins to form mRNA–protein complexes (mRNPs), but changes in the composition of mRNPs during posttranscriptional regulation remain largely unexplored. Here, we have analyzed, on a transcriptome-wide scale, how microRNA-mediated repression modulates the a...
Autores principales: | Rissland, Olivia S., Subtelny, Alexander O., Wang, Miranda, Lugowski, Andrew, Nicholson, Beth, Laver, John D., Sidhu, Sachdev S., Smibert, Craig A., Lipshitz, Howard D., Bartel, David P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664449/ https://www.ncbi.nlm.nih.gov/pubmed/29089021 http://dx.doi.org/10.1186/s13059-017-1330-z |
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