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FGF4 retrogene on CFA12 is responsible for chondrodystrophy and intervertebral disc disease in dogs

Chondrodystrophy in dogs is defined by dysplastic, shortened long bones and premature degeneration and calcification of intervertebral discs. Independent genome-wide association analyses for skeletal dysplasia (short limbs) within a single breed (P(Bonferroni) = 0.01) and intervertebral disc disease...

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Detalles Bibliográficos
Autores principales: Brown, Emily A., Dickinson, Peter J., Mansour, Tamer, Sturges, Beverly K., Aguilar, Miriam, Young, Amy E., Korff, Courtney, Lind, Jenna, Ettinger, Cassandra L., Varon, Samuel, Pollard, Rachel, Brown, C. Titus, Raudsepp, Terje, Bannasch, Danika L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664524/
https://www.ncbi.nlm.nih.gov/pubmed/29073074
http://dx.doi.org/10.1073/pnas.1709082114