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FGF4 retrogene on CFA12 is responsible for chondrodystrophy and intervertebral disc disease in dogs
Chondrodystrophy in dogs is defined by dysplastic, shortened long bones and premature degeneration and calcification of intervertebral discs. Independent genome-wide association analyses for skeletal dysplasia (short limbs) within a single breed (P(Bonferroni) = 0.01) and intervertebral disc disease...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664524/ https://www.ncbi.nlm.nih.gov/pubmed/29073074 http://dx.doi.org/10.1073/pnas.1709082114 |