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Study of in vitro transcriptional binding effects and noise using constitutive promoters combined with UP element sequences in Escherichia coli
BACKGROUND: UP elements (upstream element) are DNA sequences upstream of a promoter that interact with the α-subunit of RNA polymerase (RNAP) and can affect transcription by altering the binding RNAP to DNA. However, details of UP element and binding affinity effects on transcriptional strength are...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664571/ https://www.ncbi.nlm.nih.gov/pubmed/29118850 http://dx.doi.org/10.1186/s13036-017-0075-2 |