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Structural complexity in the KCTD family of Cullin3-dependent E3 ubiquitin ligases

Members of the potassium channel tetramerization domain (KCTD) family are soluble non-channel proteins that commonly function as Cullin3 (Cul3)-dependent E3 ligases. Solution studies of the N-terminal BTB domain have suggested that some KCTD family members may tetramerize similarly to the homologous...

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Detalles Bibliográficos
Autores principales: Pinkas, Daniel M., Sanvitale, Caroline E., Bufton, Joshua C., Sorrell, Fiona J., Solcan, Nicolae, Chalk, Rod, Doutch, James, Bullock, Alex N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664961/
https://www.ncbi.nlm.nih.gov/pubmed/28963344
http://dx.doi.org/10.1042/BCJ20170527