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Gambogenic Acid Exerts Antitumor Activity in Hypoxic Multiple Myeloma Cells by Regulation of miR-21

Hypoxia is an inseparable component of the bone marrow (BM) microenvironment, accounting for aggressive tumor behavior and poor prognosis of multiple myeloma (MM). Gambogenic acid (GNA) has proven to be an attractive option for treatment of tumors due to its tumor suppressive activity. Herein, we fo...

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Detalles Bibliográficos
Autores principales: Liu, Ping, Wu, Xue, Dai, Lu, Ge, Zheng, Gao, Chong, Zhang, Hongming, Wang, Fei, Zhang, Xiaoping, Chen, Baoan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665045/
https://www.ncbi.nlm.nih.gov/pubmed/29158801
http://dx.doi.org/10.7150/jca.19290