A novel bifunctional anti-PD-L1/TGF-β Trap fusion protein (M7824) efficiently reverts mesenchymalization of human lung cancer cells

Mesenchymalization is a cellular and molecular program in which epithelial cells progressively lose their well-differentiated phenotype and adopt mesenchymal characteristics. Tumor mesenchymalization occurs during the progression of cancer to metastatic disease, and is also associated with resistanc...

Descripción completa

Detalles Bibliográficos
Autores principales: David, Justin M., Dominguez, Charli, McCampbell, Kristen K., Gulley, James L., Schlom, Jeffrey, Palena, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665067/
https://www.ncbi.nlm.nih.gov/pubmed/29123964
http://dx.doi.org/10.1080/2162402X.2017.1349589

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665067/
https://www.ncbi.nlm.nih.gov/pubmed/29123964
http://dx.doi.org/10.1080/2162402X.2017.1349589

Ejemplares similares