Iron affects Ire1 clustering propensity and the amplitude of endoplasmic reticulum stress signaling

The unfolded protein response (UPR) allows cells to adjust secretory pathway capacity according to need. Ire1, the endoplasmic reticulum (ER) stress sensor and central activator of the UPR is conserved from the budding yeast Saccharomyces cerevisiae to humans. Under ER stress conditions, Ire1 cluste...

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Detalles Bibliográficos
Autores principales: Cohen, Nir, Breker, Michal, Bakunts, Anush, Pesek, Kristina, Chas, Ainara, Argemí, Josepmaria, Orsi, Andrea, Gal, Lihi, Chuartzman, Silvia, Wigelman, Yoav, Jonas, Felix, Walter, Peter, Ernst, Robert, Aragón, Tomás, van Anken, Eelco, Schuldiner, Maya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665437/
https://www.ncbi.nlm.nih.gov/pubmed/28794014
http://dx.doi.org/10.1242/jcs.201715

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665437/
https://www.ncbi.nlm.nih.gov/pubmed/28794014
http://dx.doi.org/10.1242/jcs.201715

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