p53-independent DUX4 pathology in cell and animal models of facioscapulohumeral muscular dystrophy

Facioscapulohumeral muscular dystrophy (FSHD) is a genetically dominant myopathy caused by mutations that disrupt repression of the normally silent DUX4 gene, which encodes a transcription factor that has been shown to interfere with myogenesis when misexpressed at very low levels in myoblasts and t...

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Detalles Bibliográficos
Autores principales: Bosnakovski, Darko, Gearhart, Micah D., Toso, Erik A., Recht, Olivia O., Cucak, Anja, Jain, Abhinav K., Barton, Michelle C., Kyba, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665455/
https://www.ncbi.nlm.nih.gov/pubmed/28754837
http://dx.doi.org/10.1242/dmm.030064

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665455/
https://www.ncbi.nlm.nih.gov/pubmed/28754837
http://dx.doi.org/10.1242/dmm.030064

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