The chromatin remodeling BAP complex limits tumor-promoting activity of the Hippo pathway effector Yki to prevent neoplastic transformation in Drosophila epithelia

Switch/sucrose non-fermentable (SWI/SNF) chromatin remodeling complexes are mutated in many human cancers. In this article, we make use of a Drosophila genetic model for epithelial tumor formation to explore the tumor suppressive role of SWI/SNF complex proteins. Members of the BAP complex exhibit t...

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Detalles Bibliográficos
Autores principales: Song, Shilin, Herranz, Héctor, Cohen, Stephen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665456/
https://www.ncbi.nlm.nih.gov/pubmed/28754838
http://dx.doi.org/10.1242/dmm.030122

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665456/
https://www.ncbi.nlm.nih.gov/pubmed/28754838
http://dx.doi.org/10.1242/dmm.030122

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