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An immunofluorescence assay for extracellular matrix components highlights the role of epithelial cells in producing a stable, fibrillar extracellular matrix

Activated fibroblasts are considered major drivers of fibrotic disease progression through the production of excessive extracellular matrix (ECM) in response to signals from damaged epithelial and inflammatory cells. Nevertheless, epithelial cells are capable of expressing components of the ECM, cro...

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Detalles Bibliográficos
Autores principales: Qureshi, Omar S., Bon, Hélène, Twomey, Breda, Holdsworth, Gill, Ford, Kirsty, Bergin, Marianne, Huang, Linghong, Muzylak, Mariusz, Healy, Louise J., Hurdowar, Vanessa, Johnson, Timothy S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665462/
https://www.ncbi.nlm.nih.gov/pubmed/29032370
http://dx.doi.org/10.1242/bio.025866