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HCN4 ion channel function is required for early events that regulate anatomical left-right patterning in a nodal and lefty asymmetric gene expression-independent manner

Laterality is a basic characteristic of all life forms, from single cell organisms to complex plants and animals. For many metazoans, consistent left-right asymmetric patterning is essential for the correct anatomy of internal organs, such as the heart, gut, and brain; disruption of left-right asymm...

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Detalles Bibliográficos
Autores principales: Pai, Vaibhav P., Willocq, Valerie, Pitcairn, Emily J., Lemire, Joan M., Paré, Jean-François, Shi, Nian-Qing, McLaughlin, Kelly A., Levin, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665463/
https://www.ncbi.nlm.nih.gov/pubmed/28818840
http://dx.doi.org/10.1242/bio.025957