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Blocking autophagy enhances the pro-apoptotic effect of bufalin on human gastric cancer cells through endoplasmic reticulum stress

Bufalin has been used to treat cancer for several years. However, the molecular mechanisms for its anti-tumor function are not fully understood. This work aimed to investigate the effect of bufalin on the proliferation and apoptosis of human gastric cancer (HGC) cells and the roles of endoplasmic re...

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Detalles Bibliográficos
Autores principales: Zhao, Hongyan, Li, Qinghua, Pang, Jie, Jin, Huilin, Li, Hongwei, Yang, Xiaoying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665466/
https://www.ncbi.nlm.nih.gov/pubmed/28838965
http://dx.doi.org/10.1242/bio.026344