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Ubiquitination of basal VEGFR2 regulates signal transduction and endothelial function

Cell surface receptors can undergo recycling or proteolysis but the cellular decision-making events that sort between these pathways remain poorly defined. Vascular endothelial growth factor A (VEGF-A) and vascular endothelial growth factor receptor 2 (VEGFR2) regulate signal transduction and angiog...

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Detalles Bibliográficos
Autores principales: Smith, Gina A., Fearnley, Gareth W., Abdul-Zani, Izma, Wheatcroft, Stephen B., Tomlinson, Darren C., Harrison, Michael A., Ponnambalam, Sreenivasan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665470/
https://www.ncbi.nlm.nih.gov/pubmed/28798148
http://dx.doi.org/10.1242/bio.027896