Cargando…
Ubiquitination of basal VEGFR2 regulates signal transduction and endothelial function
Cell surface receptors can undergo recycling or proteolysis but the cellular decision-making events that sort between these pathways remain poorly defined. Vascular endothelial growth factor A (VEGF-A) and vascular endothelial growth factor receptor 2 (VEGFR2) regulate signal transduction and angiog...
Autores principales: | Smith, Gina A., Fearnley, Gareth W., Abdul-Zani, Izma, Wheatcroft, Stephen B., Tomlinson, Darren C., Harrison, Michael A., Ponnambalam, Sreenivasan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665470/ https://www.ncbi.nlm.nih.gov/pubmed/28798148 http://dx.doi.org/10.1242/bio.027896 |
Ejemplares similares
-
VEGFR2 Trafficking, Signaling and Proteolysis is Regulated by the Ubiquitin Isopeptidase USP8
por: Smith, Gina A., et al.
Publicado: (2015) -
VEGF-A isoforms program differential VEGFR2 signal transduction, trafficking and proteolysis
por: Fearnley, Gareth W., et al.
Publicado: (2016) -
Tpl2 is required for VEGF-A-stimulated signal transduction and endothelial cell function
por: Fearnley, Gareth W., et al.
Publicado: (2019) -
The cellular response to vascular endothelial growth factors requires co-ordinated signal transduction, trafficking and proteolysis
por: Smith, Gina A., et al.
Publicado: (2015) -
VEGF-A isoform-specific regulation of calcium ion flux, transcriptional activation and endothelial cell migration
por: Fearnley, Gareth W., et al.
Publicado: (2015)