Generation of G protein-coupled receptor antibodies differentially sensitive to conformational states

The N-terminal region of G protein-coupled receptors can be efficiently targeted for the generation of receptor-selective antibodies. These antibodies are useful for the biochemical characterization of the receptors. In this study, we developed a set of criteria to select the optimal epitope and app...

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Detalles Bibliográficos
Autores principales: Heimann, Andrea S., Gupta, Achla, Gomes, Ivone, Rayees, Rahman, Schlessinger, Avner, Ferro, Emer S., Unterwald, Ellen M., Devi, Lakshmi A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665533/
https://www.ncbi.nlm.nih.gov/pubmed/29091950
http://dx.doi.org/10.1371/journal.pone.0187306

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665533/
https://www.ncbi.nlm.nih.gov/pubmed/29091950
http://dx.doi.org/10.1371/journal.pone.0187306

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