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The abundance of metabolites related to protein methylation correlates with the metastatic capacity of human melanoma xenografts
Metabolic reprogramming is a major factor in transformation, and particular metabolic phenotypes correlate with oncogenotype, tumor progression, and metastasis. By profiling metabolites in 17 patient-derived xenograft melanoma models, we identified durable metabolomic signatures that correlate with...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665593/ https://www.ncbi.nlm.nih.gov/pubmed/29109980 http://dx.doi.org/10.1126/sciadv.aao5268 |