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The abundance of metabolites related to protein methylation correlates with the metastatic capacity of human melanoma xenografts

Metabolic reprogramming is a major factor in transformation, and particular metabolic phenotypes correlate with oncogenotype, tumor progression, and metastasis. By profiling metabolites in 17 patient-derived xenograft melanoma models, we identified durable metabolomic signatures that correlate with...

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Detalles Bibliográficos
Autores principales:	Shi, Xiaolei, Tasdogan, Alpaslan, Huang, Fang, Hu, Zeping, Morrison, Sean J., DeBerardinis, Ralph J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2017
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665593/ https://www.ncbi.nlm.nih.gov/pubmed/29109980 http://dx.doi.org/10.1126/sciadv.aao5268

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