Prior alcohol use enhances vulnerability to compulsive cocaine self-administration by promoting degradation of HDAC4 and HDAC5

Addiction to cocaine is commonly preceded by experiences with legal or decriminalized drugs, such as alcohol, nicotine, and marijuana. The biological mechanisms by which these gateway drugs contribute to cocaine addiction are only beginning to be understood. We report that in the rat, prior alcohol...

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Detalles Bibliográficos
Autores principales: Griffin, Edmund A., Melas, Philippe A., Zhou, Royce, Li, Yang, Mercado, Peter, Kempadoo, Kimberly A., Stephenson, Stacy, Colnaghi, Luca, Taylor, Kathleen, Hu, Mei-Chen, Kandel, Eric R., Kandel, Denise B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665598/
https://www.ncbi.nlm.nih.gov/pubmed/29109977
http://dx.doi.org/10.1126/sciadv.1701682

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665598/
https://www.ncbi.nlm.nih.gov/pubmed/29109977
http://dx.doi.org/10.1126/sciadv.1701682

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