α-Linolenic Acid Inhibits Receptor Activator of NF-κB Ligand Induced (RANKL-Induced) Osteoclastogenesis and Prevents Inflammatory Bone Loss via Downregulation of Nuclear Factor-KappaB-Inducible Nitric Oxide Synthases (NF-κB-iNOS) Signaling Pathways

BACKGROUND: Inflammation is a major cellular strain causing increased risk of osteo-degenerative diseases. Omega-3 fatty acids have been great source in suppressing inflammation. We investigated the effect of α-linolenic acid (ALA) on RANKL-stimulated osteoclast differentiation, LPS-induced and ovar...

Descripción completa

Detalles Bibliográficos
Autores principales: Song, Jiefu, Jing, Zhizhen, Hu, Wei, Yu, Jianping, Cui, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2017
Materias:
Lab/In Vitro Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665607/
https://www.ncbi.nlm.nih.gov/pubmed/29061958
http://dx.doi.org/10.12659/MSM.904795

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665607/
https://www.ncbi.nlm.nih.gov/pubmed/29061958
http://dx.doi.org/10.12659/MSM.904795

Ejemplares similares