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Recruitment dynamics of ESCRT-III and Vps4 to endosomes and implications for reverse membrane budding

The ESCRT machinery mediates reverse membrane scission. By quantitative fluorescence lattice light-sheet microscopy, we have shown that ESCRT-III subunits polymerize rapidly on yeast endosomes, together with the recruitment of at least two Vps4 hexamers. During their 3–45 s lifetimes, the ESCRT-III...

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Detalles Bibliográficos
Autores principales: Adell, Manuel Alonso Y, Migliano, Simona M, Upadhyayula, Srigokul, Bykov, Yury S, Sprenger, Simon, Pakdel, Mehrshad, Vogel, Georg F, Jih, Gloria, Skillern, Wesley, Behrouzi, Reza, Babst, Markus, Schmidt, Oliver, Hess, Michael W, Briggs, John AG, Kirchhausen, Tomas, Teis, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665648/
https://www.ncbi.nlm.nih.gov/pubmed/29019322
http://dx.doi.org/10.7554/eLife.31652