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Recruitment dynamics of ESCRT-III and Vps4 to endosomes and implications for reverse membrane budding
The ESCRT machinery mediates reverse membrane scission. By quantitative fluorescence lattice light-sheet microscopy, we have shown that ESCRT-III subunits polymerize rapidly on yeast endosomes, together with the recruitment of at least two Vps4 hexamers. During their 3–45 s lifetimes, the ESCRT-III...
Autores principales: | Adell, Manuel Alonso Y, Migliano, Simona M, Upadhyayula, Srigokul, Bykov, Yury S, Sprenger, Simon, Pakdel, Mehrshad, Vogel, Georg F, Jih, Gloria, Skillern, Wesley, Behrouzi, Reza, Babst, Markus, Schmidt, Oliver, Hess, Michael W, Briggs, John AG, Kirchhausen, Tomas, Teis, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665648/ https://www.ncbi.nlm.nih.gov/pubmed/29019322 http://dx.doi.org/10.7554/eLife.31652 |
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