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Antitumor effects of eribulin depend on modulation of the tumor microenvironment by vascular remodeling in mouse models

We previously reported that eribulin mesylate (eribulin), a tubulin‐binding drug (TBD), could remodel tumor vasculature (i.e. increase tumor vessels and perfusion) in human breast cancer xenograft models. However, the role of this vascular remodeling in antitumor effects is not fully understood. Her...

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Detalles Bibliográficos
Autores principales: Ito, Ken, Hamamichi, Shusei, Abe, Takanori, Akagi, Tsuyoshi, Shirota, Hiroshi, Kawano, Satoshi, Asano, Makoto, Asano, Osamu, Yokoi, Akira, Matsui, Junji, Umeda, Izumi O., Fujii, Hirofumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665763/
https://www.ncbi.nlm.nih.gov/pubmed/28869796
http://dx.doi.org/10.1111/cas.13392