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Targeted gene knockdown validates the essential role of lactate dehydrogenase in Cryptosporidium parvum

Cryptosporidium parvum is a zoonotic protozoan that can cause a life-threatening gastrointestinal syndrome in children and in immunocompromised adults. Currently, the only approved drug for treatment of Cryptosporidium infections in humans is nitazoxanide, but it is not effective in immunocompromise...

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Detalles Bibliográficos
Autores principales: Witola, William H., Zhang, Xuejin, Kim, Chi Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665856/
https://www.ncbi.nlm.nih.gov/pubmed/28606696
http://dx.doi.org/10.1016/j.ijpara.2017.05.002