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Effect of Triggering Receptor Expressed on Myeloid Cells 1 (TREM-1) Blockade in Rats with Cecal Ligation and Puncture (CLP)-Induced Sepsis

BACKGROUND: Blocking of TREM-1 signaling improves survival of mice with sepsis induced by Pseudomonas aeruginosa. However, whether TREM-1 blockade has beneficial effects in polymicrobial sepsis is poorly understood. Here, we aimed to investigate the effect of modulation of the TREM-1 pathway in rats...

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Detalles Bibliográficos
Autores principales: Shi, Xiaofeng, Zhang, Yue, Wang, Hao, Zeng, Sha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665857/
https://www.ncbi.nlm.nih.gov/pubmed/29059148
http://dx.doi.org/10.12659/MSM.904386