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Zika Virus Infects Intermediate Progenitor Cells and Post-mitotic Committed Neurons in Human Fetal Brain Tissues

Zika virus (ZIKV) infection is associated with microcephaly in fetuses, but the pathogenesis of ZIKV-related microcephaly is not well understood. Here we show that ZIKV infects the subventricular zone in human fetal brain tissues and that the tissue tropism broadens with the progression of gestation...

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Detalles Bibliográficos
Autores principales: Lin, Ming-Yi, Wang, Yi-Ling, Wu, Wan-Lin, Wolseley, Victoria, Tsai, Ming-Ting, Radic, Vladimir, Thornton, Matthew E., Grubbs, Brendan H., Chow, Robert H., Huang, I-Chueh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665882/
https://www.ncbi.nlm.nih.gov/pubmed/29093521
http://dx.doi.org/10.1038/s41598-017-13980-2