Hamp1 but not Hamp2 regulates ferroportin in fish with two functionally distinct hepcidin types

Hepcidin is a small cysteine rich peptide that regulates the sole known cellular iron exporter, ferroportin, effectively controlling iron metabolism. Contrary to humans, where a single hepcidin exists, many fish have two functionally distinct hepcidin types, despite having a single ferroportin gene....

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Detalles Bibliográficos
Autores principales: Neves, João V., Ramos, Miguel F., Moreira, Ana C., Silva, Tânia, Gomes, Maria S., Rodrigues, Pedro N. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665920/
https://www.ncbi.nlm.nih.gov/pubmed/29093559
http://dx.doi.org/10.1038/s41598-017-14933-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665920/
https://www.ncbi.nlm.nih.gov/pubmed/29093559
http://dx.doi.org/10.1038/s41598-017-14933-5

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