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Hamp1 but not Hamp2 regulates ferroportin in fish with two functionally distinct hepcidin types
Hepcidin is a small cysteine rich peptide that regulates the sole known cellular iron exporter, ferroportin, effectively controlling iron metabolism. Contrary to humans, where a single hepcidin exists, many fish have two functionally distinct hepcidin types, despite having a single ferroportin gene....
Autores principales: | Neves, João V., Ramos, Miguel F., Moreira, Ana C., Silva, Tânia, Gomes, Maria S., Rodrigues, Pedro N. S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665920/ https://www.ncbi.nlm.nih.gov/pubmed/29093559 http://dx.doi.org/10.1038/s41598-017-14933-5 |
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