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Modulation of the Vault Protein-Protein Interaction for Tuning of Molecular Release

Vaults are naturally occurring ovoid nanoparticles constructed from a protein shell that is composed of multiple copies of major vault protein (MVP). The vault-interacting domain of vault poly(ADP-ribose)-polymerase (INT) has been used as a shuttle to pack biomolecular cargo in the vault lumen. Howe...

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Detalles Bibliográficos
Autores principales: Yu, Kang, Yau, Yin Hoe, Sinha, Ameya, Tan, Tabitha, Kickhoefer, Valerie A., Rome, Leonard H., Lee, Hwankyu, Shochat, Susana G., Lim, Sierin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665922/
https://www.ncbi.nlm.nih.gov/pubmed/29093465
http://dx.doi.org/10.1038/s41598-017-12870-x