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A novel peptide that improves metabolic parameters without adverse central nervous system effects

Intracellular peptides generated by limited proteolysis are likely to function inside and outside cells and could represent new possibilities for drug development. Here, we used several conformational-sensitive antibodies targeting G-protein coupled receptors to screen for novel pharmacological acti...

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Detalles Bibliográficos
Autores principales: Reckziegel, Patrícia, Festuccia, William T., Britto, Luiz R. G., Jang, Karen L. Lopes, Romão, Carolina M., Heimann, Joel C., Fogaça, Manoela V., Rodrigues, Naielly S., Silva, Nicole R., Guimarães, Francisco S., Eichler, Rosangela A. S., Gupta, Achla, Gomes, Ivone, Devi, Lakshmi A., Heimann, Andrea S., Ferro, Emer S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665932/
https://www.ncbi.nlm.nih.gov/pubmed/29093454
http://dx.doi.org/10.1038/s41598-017-13690-9