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A novel peptide that improves metabolic parameters without adverse central nervous system effects
Intracellular peptides generated by limited proteolysis are likely to function inside and outside cells and could represent new possibilities for drug development. Here, we used several conformational-sensitive antibodies targeting G-protein coupled receptors to screen for novel pharmacological acti...
Autores principales: | Reckziegel, Patrícia, Festuccia, William T., Britto, Luiz R. G., Jang, Karen L. Lopes, Romão, Carolina M., Heimann, Joel C., Fogaça, Manoela V., Rodrigues, Naielly S., Silva, Nicole R., Guimarães, Francisco S., Eichler, Rosangela A. S., Gupta, Achla, Gomes, Ivone, Devi, Lakshmi A., Heimann, Andrea S., Ferro, Emer S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665932/ https://www.ncbi.nlm.nih.gov/pubmed/29093454 http://dx.doi.org/10.1038/s41598-017-13690-9 |
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